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Creatinine was measured using the Jaffe method, and estimated glomerular filtration rate (eGFR) was calculated using the modified Modification of Diet in Renal Disease (MDRD) equation [ 19].
We also identified chronic kidney disease (estimated glomerular filtration rate <60 ml min−1 1.73 m−2) from serum creatinine values using the modified Modification of Diet in Renal Disease (MDRD) equation.
Estimated glomerular filtration rate (eGFR) was calculated using the modified Modification of Diet in Renal Disease equation based on data for the Chinese population: 175 × serum creatinine (mg/dL) − 1.234 × age (years) − 0.179 (× 0.79 if female ).
12 (4) The estimated glomerular filtration rate (eGFR) of each participant was estimated using the modified Modification of Diet in Renal Disease equation adapted for the Chinese 13 as: eGFR=186×Scr−1.154×age−0.203×0.742 (female)×1.233 (Chinese).
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Estimated glomerular filtration rate (eGFR) was calculated using the modified three-variable Modification of Diet in Renal Disease (MDRD) equation developed by the Japanese Society of Nephrology to adjust for Japanese physical characteristics: eGFR = 194 × serum creatinine− 1.094 × age− 0.287 (if female, × 0.739) [ 15].
If baseline creatinine was not available, it was estimated by assuming that glomerular filtration rate (GFR) in that given patient was 75 ml/min per 1.73 m, and serum creatinine can be estimated by using the modified 4-variable Modification of Diet in Renal Disease (MDRD) formula [ 17, 18].
In the Group A PDT was performed by using the modified CBR technique: the modification consist of a transverse cut (5 mm long and deep to the anterior tracheal wall) practiced, under guided light given by flexible bronchoscope trans illumination, before the trachea was punctured with a 14-gauge Teflon catheter introducer needle.
These values were calculated using the modified isotope dilution mass spectrometry-traceable Modification of Diet in Renal Disease Study equation.
The postsynthetic modification strategy could not be applied to oligodeoxynucleotides containing α-OH-PdG adduct 3, which were prepared using the modified phosphoramidite approach (40, 41).
The glomerular filtration rate was estimated by using a modified Modification of Diet in Renal Disease (MDRD) Study formula[ 15]: estimated GFR (eGFR, mL·min-1·1.73 m-2) = 175 × standard (Scr -1.234 Scr -1.2349 × age-0.179 age-0.179
Renal function was assessed with eGFR using modified Modification of Diet in Renal Disease Study equation for Chinese.
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