Hb was adjusted for altitude using the model published by the CDC [27], [28], [29] with the following formula calculating the correcting factor for the different Hb values: ΔHb [g/L] = −0.32 x (altitude[m] x 0.0033)+0.22 x (altitude[m] x 0.0033 2.
All simulations were carried out using the model parameters published in [ 20].
Data for the murine heart cell function was generated using the model recently published by Li et al. [ 35], built to account for the action potential and calcium transient of the cardiomyocyte in terms of its constituent ion currents and gating channels.
Using the "stabilization model" published in the reference [ 9], we here measured how much the degradation parameter of Cdc20 could be increased (i.e., the upper limit of kd20) in each of the gene-deletion models and compared the upper limit of kd20 with that in the wild type to obtain the relative change in the upper limit of kd20 (see Methods for details).
The nucleosome arrangement along all of these sequences was predicted using the thermodynamic model published by Segal et al. [ 1], who also provided a 32-bit Linux binary executable, wrapped by Perl scripts and released under the GNU LGPL, especially for this purpose [ 17].
British estimates using the updated model published by Delaney et al. suggested that 48.3% of patients diagnosed with cancer will have an indication to radiotherapy [ 11], which seems to hold true in Poland as well.
When available, we used data from Estonia as inputs, otherwise we used the default data in the model published for the US [ 10] (inputs not presented in this report are available in the online supplement of Elbasha & Dasbach, 2010 [ 10]).
Time-integrated activity in the main source organs [Ã(rs,TD)] for each radioisotope was calculated using the radiopharmaceutical biokinetic models published by the International Commission on Radiological Protection (Publication 53 and 80, ICRP).
Expected birthweight was calculated using the sex-specific models published by Marsal [17].
Using the published model for substrate mimicry by the syringolins and knowledge about the substrate preferences of the proteolytic subunits of the human proteasome, we have designed, synthesized, and evaluated syringolin analogs.
