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A GTR+Γ+I and a JC69+Γ model were selected for the cox1 and PEPCK reduced data sets, respectively, following the second-order Akaike information criterion (AICc) implemented in MrAIC, under the option using the models implemented in MrBayes [55].
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The evaluation of positive selection using the model implemented in Single Likelihood Ancestor Counting (SLAC) showed three sites under selection, one of those sites being similar to that retrieved with model M8 in PAML.
In each case, mass and energy balances were obtained using the model implemented in Aspen Plus v7.2 (Aspen Technology ,Inc, Burlington, MA, USA), and these were then used in Aspen Process Economic Analyzer v7.2 to obtain the capital cost.
Tests for heterogeneous selective pressures were carried out on the resolved phylogeny using the evolutionary models implemented in PAML 3.15 [ 39] and the complete MSA.
In addition to the FEL method implemented in HYPHY, this result was confirmed using the M7/M8 models implemented in PAML.
The dipolar evolution data were processed using the model-free approach implemented in the MATLAB-based program DeerAnalysis 2013.
Neutron-induced reactions on 27Al and 19F nuclei are investigated using the optical model implemented in the TALYS 1.4 toolkit.
Calculations were performed using the 'Multinomial Model' implemented in the software package SPADE [36], and plotted on Microsoft Excel.
A distance matrix was created using the D2S model implemented in the jD2Stat program, and a neighbor-joining phylogenetic tree was inferred with phylip v3.695.
Alternatively, we accounted for the compositional heterogeneity in the nucleotide sequences by using the nonstationary model implemented in nhPhyML-Discrete.
The electrostatic/polar solvation free energies for the proteins in the GB dataset were computed by using the GB model implemented in Amber14.
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