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A 4th investigator (an orthopaedic surgeon of 15 years, IH), blind to the goniometric measurements, measured the discrete flexion and extension angles off the radiographs using the method utilised by previous investigators [ 16, 23].
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The method utilised is that of system dynamics (SD).
Utilising a small parameter resulting from the ratio of these two timescales, we construct asymptotic solutions using the method of matched asymptotic expansions.
Regarding only CRC as the cancer of interest, the completeness of CRC prevalence in the CNCR can be estimated, using the model-based method utilising the observed and modelled CRC prevalence [ 9], to be approximately 97% in 2008.
We used an established method, utilising the cost subcategories, to calculate which costs are dependent on LOS [ 20].
The units of services used will be based upon local costs of services and include allowances for managerial and premises overheads and the costs associated with training and supervision using methods utilised in similar intervention studies [ 32].
Antibodies against CT-P13 or INX were measured using an electrochemiluminescent immunoassay method utilising the Meso Scale Discovery platform (MSD, Rockville, Maryland, USA).
TC, TG and HDL were analyzed using the enzymatic colorimetric method utilising esterase-oxidase and oxidase-peroxidase, using 5 mL of serum after being centrifuged at 3,000 rpm for 5 minutes.
Otherwise, a fixed-effects model using the Mantel–Haenszel method was utilised (Petitti et al, 1994).
Previous research utilised a neural network structure manually optimised using the Taguchi method with the connection weights trained using the Backpropagation rule.
Both programs infer CNV states from array data based on LRR and BAF; the difference between the two methods is the iterative mathematical methods utilised: QuantiSNP uses an objective Bayes hidden-Markov model, while Nexus SNPRank uses a segmentation algorithm (a variation of the circular binary segmentation) that recursively divides chromosomes into segments of common intensity distribution.
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