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Using the median effect method showed that phenanthrene and GTP were antagonistic when the inhibitory levels were less than about 50%.
HL-60 myeloid leukemia cells were used for in vitro studies of the combination of JS-K with daunorubicin (DAUNO), cytarabine (ARA-C) or etoposide (ETOP) using the median effect method to determine synergistic, antagonistic, or additive effects.
The antiviral EC50 and cytotoxic concentrations (CC50,) was determined from the concentration response curve using the median effect method [20].
Synergy was determined using the median effect technique (Chou and Talalay, 1987, pp 37 64).
Combination index (CI) values were calculated using the median effect analysis method.
To evaluate drug combination effects we analyzed cytotoxicity assay data using the median effect method by Chou and Talalay [ 22].
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The results were analyzed using the median effects analysis of Chou and Talalay [36], and the combination index (CI) derived using the Calcusyn software program (Biosoft, Cambridge, United Kingdom).
The nature of the interactions between these compounds and gemcitibine, 5-fluorouracil, or camptothecin was evaluated using the median effects analysis of Chou and Talalay, and the combination index (CI) derived, with a CI<1 indicating a synergistic interaction.
To determine whether the combination treatment is synergistic, the combination index (CI) was calculated using CalcuSyn software (Biosoft, Cambridge, UK) that uses the median effect principle.
Viewing the data conservatively, for the present paper we will use the median effect size of -.32 as typical of published studies.
Interaction of drugs was analysed using the median-effect method of Chou and Talalay.
More suggestions(15)
using the median method
using the median percentile
using the median estimate
using the median polish
using the median test
using the median sale
using the median operator
using the median value
using the median rating
using the median multiple
using the median normalization
using the median storage
using the median filter
using the median height
using the median inhibitory
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