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To adjust for underestimation of rates using the linked datasets, and to correct for any linkage bias whereby the percentage of eligible cancer records linked varied by socio-demographic characteristics, we calculated weights for strata of age, sex, ethnicity, region, small area deprivation, and time since census.
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The English NHS Central Office for Research Ethics Committees approved the current work programme of analysis using the linked dataset (reference number 04/Q2006/176).
Further research is planned to link the TILDA dataset to the national prescribing database (HSE-PCRS) to facilitate the application of 19 additional STOPP criteria and to estimate the cost of PIP using these linked datasets.
We thank staff in the Centre for Epidemiology and Research: Kim Lim for management of the linked datasets and checking programmes used in the analysis, and George Doukas for administering the datasets held on the Health Outcomes and Information Statistical Toolkit HOISTT) data warehouse.
All direct identifiers, as well as any characteristics that might lead to identification, were omitted from the linked dataset used in the present study.
The linked dataset used for our study remained representative of the GPRD overall, as whole practices rather than individual patients declined or consented to the linkage.
For the linked dataset, we used the same principal diagnosis range and admission source category as those for unlinked data, but disregarded discharge status.
The main benefit of using additional linked datasets, like the NBSS, is that it makes use of precise information recorded about the individuals of interest.
Making predictions using weakly linked datasets is of utmost interest for plant breeders.
With permission from data stewards at the BC Ministry of Health Services and the College of Pharmacists of BC, and the approval of the University of British Columbia research ethics board, we conducted this study using de-identified linked datasets from Population Data BC and BC PharmaNet.
Design Cohort study using a linked dataset.
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