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Tests of association were performed using the likelihood methods implemented in UNPHASED v3.0.10 [54], which can analyze samples of nuclear families, unrelated subjects, or a combination of both.
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Estimation of the model parameters may then be carried out using the likelihood method.
Table 3 lists the final multivariable model fitted using the likelihood method and the exact method.
Paternity analysis (the assignment of a putative father to a genetically known mother-offspring pair) was performed using the likelihood method implemented in the program FAMOZ [ 30].
We also fitted geographic clines to each locus separately and assessed cline coincidence using the likelihood method described by Phillips et al. [ 50].
To estimate the DFEs (DFE, i.e., the distribution of the strength of selection acting against new mutations) and the proportion of adaptive substitutions in A. kamchatica, A. halleri, and A. lyrata, we used the likelihood method implemented in the software DoFE 3.013.
In the reinforcement learning setting, gradients of the policy can still be obtained using the likelihood ratio method.
Model reduction was performed using the likelihood ratio method.
The final model was derived by using the likelihood ratio method (22 ).
We estimated 95% confidence intervals for the parameters using the likelihood ratio method [ 34].
Confidence intervals for QTL location were calculated using the Likelihood drop method [ 43].
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