Sentence examples for using the ld model from inspiring English sources

Define the following disease penetrances: We can relate the penetrances at the two SNPs by using the LD model.

Using the LD model, The determinant,, is exactly 0 for a two-SNP multiplicative model and is a convenient measure for the deviation from it.

The same priors were used for the inference of parameters of the DD model from all realisations of the model, and, similarly, a fixed prior was used for the LD model and in the analysis of alternative values for N.

Linkage disequilibrium (LD) calculations between polymorphisms were carried out using the LD option implemented in TASSEL v.2.1 [ 30].

Founder haplotypes in the pedigree were generated using the estimated LD model.

This includes 10 independent replicates of LD model fitting and association testing (The LD model fitting used 30 EM steps and the number of upper-layer clusters S = 2 and the number of lower-layer clusters K = 10).

To determine whether this pathway was activated in the LD model, the amount of phosphorylated-Src was measured using western blot.

We applied the RFMix algorithm (Maples et al. 2013), which uses a LD model between markers to infer ancestry for each segment of the genome between a mixture of two putative ancestral panels of haplotypes.

LD between the two SNPs was measured using the pairwise LD measures D' and r2 and LD blocks were subsequently defined using the Gabriel et al algorithm [19].

Using the linear model, we were able to explain the occurrence of unusually large and small values of DI as being due to a sudden shift at CT 13 in LD of model slopes (AV values).

Single-SNP logistic regression using the correct analysis model performed worse than using a multiplicative analysis model, as previously demonstrated [Iles, 2010] for SNPs in low LD with a causal SNP.