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Following a secondary intention-to-treat analysis using the last observation carried forward procedure, symptom change over time was still significant (data not shown).
Using the last observation carried forward, no statistically significant treatment differences were found.
Missing data were imputed using the last observation carried forward method.
Twenty survivors were lost to follow-up and missing data were imputed using the last observation before discharge.
Using the last observation carried forward, the mean total YBOCS score decreased from 23.9 at baseline to 17.6 at the final visit (p =.06).
Patients who received a surgical reintervention were considered treatment failures, and their subsequent data was imputed using the last observation carried forward (LOCF) method.
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Missing values were imputed using the last-observation-carried-forward approach.
Missing data for efficacy variables were imputed using the last-observation-carried-forward (LOCF) method.
Missing values of participants were imputed using the last-observation-carried-forward method [ 36].
Mean changes from baseline to endpoint were analyzed using the last-observation-carried-forward approach.
Missing secondary efficacy variables were replaced using the last-observation-carried-forward (LOCF) approach.
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