Sentence examples for using the intracardiac injection from inspiring English sources

To our knowledge this is the first xenograft model of metastasis using the intracardiac injection of BC cells in combination with engineered bone, although this inoculation technique is widely used in traditional xenograft models of metastasis to the mouse skeleton.

Systemic tumor burden to distant bony and soft tissue metastatic sites was greater in the G3 group using the intracardiac injection metastatic model Versican G3 domain appears to be important in local and systemic tumor invasiveness of human breast cancer.

In this study, to clarify the role of RANKL-induced osteoclast formation and MMP-dependent matrix degradation in osteolysis because of bone metastasis, we examined the expression of RANKL and MMPs in bone with metastasis using the intracardiac injection of breast cancer cells.

The intracardiac injection model is used to generate widespread arterial dissemination of tumor cells by bypassing the lungs in order to seed cells to various organs.

A limitation of the intracardiac injection metastatic model used in the present study is that it bypasses the step of initial establishment of a local tumor with secondary circulatory seeding.

They also developed pulmonary and bone tumours after the intracardiac injection.

They also developed pulmonary, liver, brain and bone tumours secondary to the intracardiac injection of W256 cells.

The median survival time after the intracardiac injection of 2 × 10 and 10 cells was 26 and 29 days, respectively (P = 0.20).

Rats were sacrificed by asphyxiation with CO2, 9 days (F344) or 15 days (COP) after the intracardiac injection of tumour cells.

Secondly, the intracardiac injection model does not recapitulate the requirement for cells to escape the primary site and so not all the steps of the metastatic process can be studied.

We first sought to evaluate the metastatic potential of the mouse cell line using intracardiac injections.