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The reference dataset was used as the hypothesis generating dataset, and genes with a FDR adjusted p-value < 0.1 were included in the gene set that was subsequently validated using the independent validation dataset.
b) Density plot of the differences between the observed values and the predicted values using the independent validation set.
Figure 6 a) Plot of experimental versus predicted values of enthalpy of formation of gas phase (kJ/mol) using the independent validation set.
The experimental values of enthalpy of formation of gas phase (kJ/mol) were compared to the predicted values using the independent validation set and represented in a scatter plot, with an RMSE of 48.64 and a Q2 of 0.9607 (Figure 6a).
The performance of the two algorithms is evaluated here using the independent validation set described in Methods section.
Finally, the accuracy of the models to predict CH and CRF was tested using the independent validation data made up of 43 normal participants.
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Finally, we used the independent validation set to determine the accuracy of the predictor.
Hence, SF-model's final assessment was performed using of the independent validation set (IVS).
The microarray and clinical data used for the independent validation testing set analysis were obtained from the GEO database with accession number GSE2990.
We also collected from ArrayExpress [ 22] the dataset used to retrain this signature on the custom array currently used in the MammaPrint assay [ 3] as well as the independent validation cohort using the same array [ 19].
Table containing information about the structure (NIST Web book/CRC ID, CASRN, compound name and SMILES), the corresponding experimental values for the standard molar enthalpy of formation (kJ/mol) of gas phase at 298.15 K and the complete list of molecular descriptors for the compounds in the independent validation set used in this study.
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using the independent Student t-test
using the independent computing
using the French validation
using the same validation
using the independent modal
using the second validation
using the independent platform
using the independent sampling
using the transgenic validation
using the independent codeword
using the independent simplest-test
using the full validation
using the independent sample
using the discriminant validation
using the independent sector
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