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Proposed copula-based prediction model has been validated using the independent bootstrap samples.
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The amino acid sequences were aligned using ClustalW program and phylogenetic tree was developed using MEGA (Molecular Evolutionary Genetics Analysis) software with neighbor joining method using 500 independent bootstrap runs [ 42].
The reliability of internal branches was assessed using the bootstrapping method (400 bootstrap replicates).
Node support of phylogenetic tree was assessed using the bootstrap method with 100 bootstrap replicates.
E[ p] is the expected value of p using the bootstrap technique for 100 000 bootstraps.
5 Ninety-nine perCIst CIs were calculated using the bootstrap percentile method with 2,000 bootstrap samples.
95% CIs are computed using the bias-corrected bootstrap method using 1000 bootstrap samples.
Capwire calculates 95% CIs using the parametric bootstrap [27].
Standard errors were computed using the nonparametric bootstrap as above.
ML branch support was assessed via 100 nonparametric bootstrap pseudoreplicates, using the "rapid" bootstrap approach.
Bootstrap values were calculated using the rapid bootstrap method and CAT model with 100 replicates.
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