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Gene ontology analyses were performed using the GREAT package [ 30].
Gene Ontology (GO) analyses for biological processes were performed using the GREAT package [ 115].
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UCSC Table Browser was used to obtain genomic sequences, and were considered to contain an κBRE if their genomic sequences contained at least one site matching the NF-κB (Hsapiens-JASPAR_2014-NFKB1-MA0105.3) JASPAR motif with a score of 90% or greater, as determined using the Biostrings package in Bioconductor59.
The statistical analysis were performed using the R statistical package and the effsize package (Torchiano 2017).
Models were fitted using the lme471 package.
Solubility and supersaturation were calculated using the software package EQ3/6.
The data was plotted using the rworldmap package in R63.
Data were analyzed using the R package.
Analysis was done using the same package.
and R using the lumi package [ 27].
We detected recombination using the RDP3 package.
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