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HH accurately detected the ∼1 Mb genomic interval encompassing the causative gene UBIAD1 using the genotypes of only four affected subjects.
We applied HH to identify the known locus using the genotypes of 10 affected subjects of a family with a rare dominant eye disease SCCD.
The HH approach was validated using the genotypes of patients from a family affected with a rare autosomal dominant disease Schnyder crystalline corneal dystrophy.
We simulated phenotypes using the genotypes of the NFBC data.
G was constructed using the genotypes of all 278 lines.
Current routine genomic evaluation of cattle populations is performed using the genotypes of ~54 000 SNP.
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Thus, we predicted the genotype of the inversion for 150 HapMap individuals using the genotype of these SNPs, and we confirmed our predictions by FISH analysis in a subset of these samples.
The chromosome arrangement for each haplotype was also determined in the same way using the genotype of the In 2L) t genetic marker.
We used the genotypes of these inferred parental individuals to obtain estimates of genetic variability.
We use the genotypes of 184 partially inbred mice from the CC lines (Aylor et al. 2011).
In this analysis, we used the genotypes of progenies to estimate the mating system parameters of the maternal parent in the field using the Expectation-Maximization method [ 37].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com