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In light of the completion of the genome sequences of M. tuberculosis and M. bovis and the experimental advances since the seminal studies of Smith, Koch and von Behring, it is now opportune to revisit their early studies of human and tubercle bacilli using the genome sequenced strains of M. bovis and M. tuberculosis.
We therefore sought to revisit the virulence of M. tuberculosis for bovines using the genome sequenced type strain, M. tuberculosis H37Rv, the best characterized strain of M. tuberculosis currently available.
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Using the genome sequence of strain EIB202 as the reference, we compared the genomic structure among the eight strains by contig mapping.
Since no complete genome sequence exists for sunflower, cDNA microarray analysis could only be performed using the genome sequence of another crop.
To analyze the relationship of the Neandertals to a more diverse set of modern humans, we repeated the analysis above using the genome sequences of the French, Han, Papuan, Yoruba, and San individuals that we generated (SOM Text 9).
Briefly, a 70-mer oligonucleotide microarray constructed using the genome sequence of S. Typhimurium strain SL1344 was used for hybridization with the cDNA of each strain.
This study examined the genome arrangement of A. actinomycetemcomitans using the genome sequences of serotypes a-c strains.
At last, the generated transcriptome was assembled by using the genome sequences of pea aphid as a reference set.
To test this we performed sequential inoculation experiments, identifying races using the genome sequences to create race-specific DNA markers.
Recently, Loke et al. [ 4] analyzed mRNA polyadenylation in Arabidopsis using the genome sequence and all available cDNAs.
Draft models were constructed using the genome sequences of P. stipitis (CBS 6054) [ 20], and P. pastoris (GS 115) [ 19].
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