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Exact(13)
For SNPs that were selected by more than one strategy and that pertained to a specific gene, we perused Entrez Gene (paying attention to the Process listed in Gene Ontology) and also queried PubMed using the gene name and Parkinson's disease, in order to identify if there is any hint of biological plausibility or evidence relating these genes specifically to Parkinson's disease.
First, a list of BUB1-, BUB1B- and/or MAD3-related articles was obtained by searching PubMed using the gene name.
This was determined by performing a Medline search using the gene name and TGF-β as keywords.
Search for genes involved in regulatory experiments can be done using the gene name, function, product, accession number, or any other GenBank annotation.
If we fail to find a UniProt ID, we search NCBI gene using the gene name or synonyms in combination with the organism name.
Briefly, the manual curation protocol involved searching PubMed (40) using the gene name (including synonyms) with accompanying text 'cancer' and 'expression'expression
Similar(47)
Candidate genes were identified via literature searches using the gene names.
Performing PubMed searches identified protein functions using the gene names with absolute changes ≥1.5-fold and P-values ≤0.001.
As we used the gene name to represent the protein, the gene-protein discordance caused by events such as alternative splicing is currently not considered.
To avoid unnecessary confusion, we continue to use the gene name xrep-1 and its corresponding protein name XREP-1 instead of wdr-23 and WDR-23 unless necessary for clarification.
Critically, in the related-species promoter sets, we use the gene name from the orthologous gene in the key species as the gene name for a promoter.
More suggestions(15)
using the element name
using the gene hierarchy
using the stage name
using the gene knockout
using the gene expression
using the gene association
using the gene ontology
using the gene pulser
using the gene sequence
using the gene replacement
using the gene symbol
using the gene database
using the gene predictor
using the gene prediction
using the gene length
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com