The patients were assessed using the following instruments at pretreatment baseline, post-treatment, and 12 months after completion of the group-CBT.
Symptoms were evaluated using the following instruments: the Hamilton Anxiety Rating Scale [16]; the Hamilton Depression Rating Scale [17]; the Fatigue Severity Scale [18]; the Chalder Fatigue Scale [19]; the Visual Analog Scale for Fatigue [20]; and the Epworth Sleepiness Scale [21].
The prepared hydrochars were characterized using the following instruments: Fisons instruments EA 1108 CHN analyser (Fison Instrument, Crawley, UK) was used for CHN analysis; samples were ground into fine powder, weighed into tin capsules and placed on the autosampler for analysis.
Patients were assessed using the following instruments: Psychotic Symptom Rating Scales [ 11].
Assessments were conducted using the following instruments: - Zarit Burden Interview (ZBI) [ 64], adapted and translated into Spanish and validated in Chile [ 65].
The stomatognathic system was examined using the following instruments: tongue depressors, dental mirror (sterilized), spotlight and front chair for onsite examination.
Upon completion of incubation, the reaction mixtures were loaded onto a 96 well plate and analyzed by Guava using the following instrument settings: Forward Scatter Gain - x8, Side Scatter – 500 V, Green Fluorescence – 413 V, Yellow – 403 V, Red – 701 V, and medium sample flow rate – 0.59 µl/s.
YFP fluorescence was measured using the following instrument settings: CW-lamp excitation filter, HQ505/10x (centered at 505 nm with a 10 nm bandpass); emission filter, F535 (centered at 535 nm with a 25 nm bandpass); CW-lamp energy, 7000; integration time, 0.3 s; emission aperture, damp; counter position, top.
All MS spectra were collected using the following instrument parameters: one microscan, 3 m/z isolation window, default charge state of +10, monoisotopic precursor selection 'enabled'enabled
The mean and standard deviation (SD) of the vesicle size distribution were recorded using the following instrument parameters: temperature, 23°C; viscosity, 0.933; refractive index, 1.333; intensity set point, 300 KHz; channel width, 10 μs; scattering angle, 90°; run time, 5 min; mode, vesicle; and Gaussian distribution.
MS peptide profiling was performed using the following instrument settings: reflector mode, positive voltage polarity, pulsed ion extraction delay 20 ns, ion source voltage "1" 25 kV, ion source voltage "2" 21.7 kV, reflector voltage "1" 26.3 kV, reflector voltage "2" 13.8 kV, reflector detection voltage 1.732 kV, sample rate 0.5 GS/s.
