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To determine the significant differences between experimental groups, ANOVA or Mann-Whitney U-tests were performed using the fold change scores.
A heat map was generated using the fold change estimates and averaged across samples.
Comparisons were made between the gastrocnemius and quadriceps muscles using the fold change threshold method.
All heatmaps were produced in R, using the fold change of normalized reads versus mean expression of the six strains.
Upregulated and downregulated miRNAs/mRNAs were identified using the fold change values (log 2) based on the control sample.
Logarithmic transformation was performed on fold change values before being statistically analyzed, using the fold change values of three replicates for each gene measured.
Similar(47)
The best performing signature, however, comprised 57 genes derived using the fold change-based z-test.
We could use the fold change as a measure of effect size, with a confidence interval or highest posterior region used to indicate the uncertainty in the estimate.
To select the DE genes, we used the fold change rank ordering statistics (FCROS) method (Dembele and Kastner, 2014).
The test statistic of Wald-Log not only uses the fold change (on log scale), but also considers the variances associated with FC.
We used the fold change of 1.3 as the threshold value to identify modulated genes as derived from the ROC curve analysis.
More suggestions(15)
using the fold technique
using the taxonomy change
using the climate change
using the spectrum change
using the fold prediction
using the time change
using the stock change
using the flow change
using the phase change
using the fold induction
using the land change
using the shot change
using the volume change
using the color change
using the porosity change
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