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The problem is resolved using the Excel solver.
Sm isotopic compositions were iteratively solved to minimize the residual sum of squares between corrected 143Nd/144Nd ratio of Sm-doped Nd standard solution and the unspiked value using the Excel Solver.
Error minimisation between calculated and experimental concentrations was carried out using the Excel Solver Add-in.
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For each corresponding P-V data set, we used the Excel "Solver" function to find itting parameters that best described the measured P-V curve.
We use the Excel "Solver" to estimate the parameters that define the mass transfer coefficient by minimizing the deviations in water content between calculation and a calibration drying experiment.
For general quality control of peptides in our laboratory, we use the Excel solver algorithm to optimize two sets of three parameters from this equation (Tmax, z (= D), and peak intensity), describing the two kinetic events of the HTT and the LTT (Fig. 2).
More precisely, the method is based on the use of the Excel Solver program.
The Excel Solver is introduced and illustrated for solution of nonlinear equations and for unconstrained and constrained linear and nonlinear programming problems.
The model was fitted iteratively using MS Excel Solver.
Due to the nonsmooth nonlinear nature of the problem addressed, a preliminary implementation was undertaken using the evolutionary solver of Excel 2010 that combines genetic algorithms and local search optimization methods.
Best estimates for parameters Vmax, b and c were obtained by minimizing residual sums of squares between predicted and observed tumor volumes using Excel Solver.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com