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The relative tolerability of various migraine interventions were assessed by using the endpoints of all-cause withdrawal and withdrawal due to adverse events.
Acid dependent cytotoxicity was also investigated in a murine solid tumour using the endpoints of growth delay and colony formation in vitro following treatment in vivo.
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In 2011, we reported that a single dose of the bivalent HPV vaccine could be as efficacious as three doses of the vaccine using the endpoint of persistent HPV infection accumulated over the first four years of the trial; findings independently confirmed in the GSK-sponsored PATRICIA trial.
We obtained a qualitatively similar result using the endpoint of baseline FEV1/FVC ratio, although the relationship was not statistically significant.
In addition, a comparative trial between a licensed vaccine and a new vaccine using the endpoint of prevention of clinical illness would require an unfeasibly large sample size.
Older studies using the endpoint of N balance or body composition provide less relevant information during the initial phase of critical illness due to the hemodynamic instability of the patient [ 15, 114].
This review uses the endpoints of local control and overall survival from randomised trials in small and non-small cell lung cancer, head and neck cancer, oesophageal cancer, rectal and anal cancer.
All VAS and TTO data were converted to scores ranging from 0 to 1. Respondents were removed from the analyses if they gave all health states the same valuations, or if they used the endpoints of a scale only.
The present study used the endpoint of hypothermia to investigate opioid and neuropeptide FF (NPFF) interactions in conscious animals.
Sample size was calculated using the primary endpoint of RFS assuming proportional hazards and exponential distributions of RFS.
Viral titers were determined using the median endpoint of the tissue culture's infectious dose (TCID50).
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