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Testing association of microbiome composition with environmental covariates is performed using the distance matrix.
Using the distance matrix, different dendrograms were created using the neighbour-joining algorithm.
When the data are sequences, using the distance matrix unavoidably results in some loss of information.
Data were ordered and grouped using the distance matrix computation and hierarchical clustering analysis calculated by MultiExperimentViewer [ 82].
A cladogram was then constructed using the distance matrix described above based on the neighbor-joining (NJ) algorithm [ 54].
We built simple phylogenetic trees for each gene group with the UPGMA method using the distance matrix information from LocARNA.
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We also perform a principle coordinate analysis using the distance matrices and plot the samples on the first two principle coordinates (Fig. 5).
Using the distance matrices separately derived for the five features, we generated UPGMA (Unweighted Pair Group Method with Arithmetic mean) trees [ 47] by the "neighbor" program in the Phylip package [ 48].
To perform a cluster analysis, we used the distance matrix of the Jaccard coefficient and Unweighted Pair Group Method with Arithmetic mean (UPGMA).
For rearrangement phylogeny, we used the distance matrix computed with the above formula with SA sequences and BIONJ to obtain a phylogenetic tree.
We also used the distance matrix generated with Gegenees, from the evolutionary distance based on the similarity between the strains, to determine how well the similarity heatplot correlated with the phylogenetic relationships reported in the literature [ 1, 12].
More suggestions(15)
using the resolvent matrix
using the distance map
using the distance equation
using the distance parameter
using the membership matrix
using the distance consistency
using the distance program
using the correlation matrix
using the distance transformation
using the distance sampling
using the distance neighbour-joining
using the dot matrix
using the design matrix
using the transformation matrix
using the distance software
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