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Molecular dynamics simulation was carried out using the Discover and Amorphous Cell module of Material Studio 4.3, developed by Accelrys Software , Inc(10188 Telesis Court, Suite 100, San Diego, CA 92121, USA).
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The structure of the ligand was appropriately modified with the Builder module and the inhibitor-enzyme complex was optimized using the Discover program and cff97 force field.
Specifically we have compared the results obtained using the DISCOVER codec, the PRISM codec and one configuration of H.264/AVC, with GOP2 in IBIB mode.
For example, he said, Disney may use the Discover name in science- and technology-oriented exhibits at Walt Disney World's Epcot Center in Orlando, Fla., and in programming for the Disney Channel.
Of note, none of the tumor expression profiles of MDACC-701 overlap with the datasets used to discover and characterize the immune metagenes in Nagalla et al. [ 36].> -wrap-foot> FAC = cyclophosphamide, doxorubicin, 5-FU; FEC =5-FU, epirubicin, cyclophosphamide; HER2-E, HER2-enriched; LumA = luminal A; LumB = luminal B; pCR = complete pathologic response; RCB = residual cancer burden.
Thus, Sanford's suggestion that Jefferson viewed men as using reason "to discover and practice the moral law" to expedite moral progress (Sanford, p. 77) is problematic.
This review will give an overview of the current knowledge of inversions in the human genome, the methods used to discover and type inversions, and their role in human disease and human genome architecture.
The same encoder generates the key frames used by the DISCOVER and progressive DVC systems.
Furthermore, the models can be used to discover and assess the effect of interventions on a disease state that may restore the system to a normal state and thus be of therapeutic value.
Thus, the resultant pharmacophore can be used to discover and design the SIRT2 inhibitors with desired biological activity.
In this paper, the DEMATEL (DEcision MAking Trial and Evaluation Laboratory) method was used to discover and illustrate the key services needed to attract SIP users and SIP providers to an SIP Mall.
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