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In a more independent test using the directory of useful decoys (DUD) set, the enrichment ratio given by these two parameters when combined with docking scores was improved to 200 300% as compared to that using scoring function alone.
For example, Liebeschuetz et al. [21] evaluated the pose prediction and the performance of Gold scoring functions using the Directory of Useful Decoys (DUD) dataset [22], which consists of 40 varied protein targets.
Here, the performance of four popular virtual screening programs, Gold, Glide, Surflex and FlexX, is compared using the Directory of Useful Decoys-Enhanced database (DUD-E), which includes 102 targets with an average of 224 ligands per target and 50 decoys per ligand, generated to avoid biases in the benchmarking.
You might begin your search for help using the directory of the Alliance of Professional Health Advocates, a trade group.
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Ms. Pierz said she expected the number of people using the directory to grow steadily over the next four years.
We used the directory of useful decoys (DUD) [23] dataset to retrospectively compare ePlatton and data fusion methods.
As database for the approach B experiments, we use the Directory of useful Decoys that is designed to avoid bias in docking and screening studies.
Next, we use the Directory of Useful Decoys, Enhanced (DUD-E) to evaluate the performance of Vina in virtual screening.
Subsequently, we use the Directory of Useful Decoys, Enhanced to demonstrate that the optimized docking box size also yields an improved ranking in virtual screening.
Alternatively, you might want to look at a range of agencies before selecting one, so it may be helpful to use the directory on the Web site of the Recruitment and Employment Confederation, the body which represents the private recruitment industry and promotes good practice.
Alternative analyses can be displayed by changing the default mapping directory, using the "Directory" function.
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