Sentence examples for using the decoy receptor from inspiring English sources
Taken together, the targeting strategy for sequestration of LPS/MD-2 complex using the decoy receptor TOY is effective in treating LPS- and bacteria-induced sepsis; furthermore, the strategy used in TOY development can be applied to the generation of other novel decoy receptor proteins.
Background: IL-13 signals via a high-affinity receptor that includes IL-4Rα and IL-13Rα1 and binds to the decoy receptor IL-13Rα2.
Beta-arrestin but not G protein-mediated signaling by the "decoy" receptor CXCR7.
The decoy receptor could also compete with the full-length receptor for ligand binding.
IL-1R1 and the decoy receptor IL-1R2 are expressed in osteoclasts.
Like TRAIL, the decoy receptor TRAIL R4 was associated with CD68-positive cells mainly in the synovial lining.
Moreover, the authors found that sT1/ST2, the decoy receptor for IL-33, had no effect on arthritis [ 1].
Therefore, the trial of blocking TLR4 using a decoy receptor in preventing sepsis under in vivo conditions has not been achieved until now.
In this regard, blocking TLR4 signaling activation using a decoy receptor could be an effective way to prevent LPS- or Gram-negative bacteria-induced sepsis if applied prior to or after challenge.
Resistance due to up-regulation of the decoy receptors can be simply overcome by using targeted agonistic antibodies.
The decoy receptors TRAIL-R3 and -R4 were barely detected in both cell lines.
