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Additional file 11: Functional annotation of precursor proteins using the DAVID service.
[ 57, 58] These 770 accession numbers were further studied in a GO term enrichment analysis using the DAVID service.
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Functional annotation clustering analyses (GO and KEGG) were performed using the DAVID web service [ 50] accessed via python scripts.
To further study the function of H19 and its role in disease, the miRSponge database was searched using the key word 'H19' and multi-context functional enrichment analysis was performed using the DAVID API service that is accessible from the database.
A gene ontology (GO) analysis was performed using the DAVID website.
Using the DAVID functional annotation clustering tool, the up- and down-regulated genes can be categorized into 176 and 146 overlapping functional gene clusters, respectively.
Differentially expressed genes were categorized in GeneOntology groups using the DAVID tool (http://david.abcc.ncifcrf.gov/).abcc.ncifcrf.gov/
Functional clustering was performed using the DAVID database.
We analyzed the 1,817 genes that were hypermethylated only in RL cells using the DAVID interface (http://david.abcc.ncifcrf.gov/).abcc.ncifcrf.gov/
Functional annotation and enrichment analyses were done using the DAVID platform version 6.7 (http://david.abcc.ncifcrf.gov/home.jsp) [36], [37].
The Gene Ontology (GO) terms and KEGG pathways of targeted genes were annotated using the DAVID gene annotation tool (http://david.abcc.ncifcrf.gov/UTH).abcc.ncifcrf.gov/UTH
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