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Screening using the cutoff levels of SF and PAI-1 may be useful and shows high sensitivity in predicting postoperative VTE in the early phase after THA.
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When divided into groups of high- and low-expressing tumours (median used as cutoff level), a Kaplan – Meier analysis showed a tendency for a nonsignificant survival benefit for patients with high LRIG1-expressing tumours.
Sensitivity and specificity to detect bone metastases were calculated using the cutoff level with the highest diagnostic accuracy obtained from ROC analysis.
In this study, only 78%and68%8% of the low-expressing genotypes accounted for deficient serum levels using the cutoff values of <50 ng/mL and <100 ng/mL, respectively (Supplementary Table 4).
The importance scores that are generated by RF take into account both main effects of variables and interactions between variables, and the most negative value of all importance scores can be used as the cutoff level for declaring SNP effects as significant.
The median value of each angiogenic factor expression was used as the cutoff level to divide patients into low- and high-expression groups.
Variation in bias of PSA measurements by these assays (Roddam et al, 2006) is likely to have affected a very small proportion of men, as the GPs were not using the same cutoff levels.
Technical issues, the cutoff levels used to classify a gene as amplified or deleted and different quality assurance guidelines could also explain these discrepancies [ 21, 22].
However, at the cutoff levels used in this study, we did not see any overlap between the transcripts that underwent alternative splicing and genes that showed altered message levels upon RBM47 reintroduction.
By using this cutoff level we could identify all the duplicates, which we expected based on the annotations.
The tumor size was grouped using 5 cm as the cutoff level, which was the threshold of indicating small HCCs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com