It would be interesting to see if other clinicians, already using the ICF, have experienced similar difculties when using the core set format and to learn how they have sought to overcome any challenges.
Treatment efficacy was assessed by using the core set of criteria for symptomatic improvement in AS as suggested by the Assessment of SpondyloArthritis international Society (ASAS) [ 26], with a 20%, a 40% response, and an improvement in five out of the six criteria.
As another independent positive set we used the core set of protein complexes from a newly published TAP-MS experiment (Gavin et al., 2006), one of the most comprehensive genome-wide screens for complexes in budding yeast.
We first performed this analysis using the core gene set of 182 genes that were consistently up-regulated or downregulated in cancer cell lines.
Our validation results using the core test set indicated that the data normalized using gdChip package perform consistently compared to those normalized by the original Windows dChip in terms of the subtype assignments.
The ML tree inferred using the core gene set roots at the midpoint, separating P. canoris, P. cangingivalis, P. bennonis, Porphyromonas somerae, and Porphyromonas levii from the other Porphyromonas species (fig. 1).
However, when the CTM and TTM were compared using the core temperature setting of the thermometer, the bias (LOA) increased to -0.97°C (-1.6 to -0.4°C), creating a larger bias than the unadjusted TTM.
First, sequence similarity searches using BLAST [44] were performed using the core ITS data set against all sequences in INSD, and matching insufficiently identified sequences were retrieved starting from the top of the BLAST results progressing until no further earth tongue genera appeared.
We also interrogated our transcriptome data using the "core xylem gene set" identified in Arabidopsis by Ko and colleagues [ 42].
Validation of the digital expression (FPKM) profiles using the "core xylem gene set" identified in Arabidopsis [ 42] has precedence in similar investigations in conifers [ 46], cotton [ 47] and poplar [ 43].
