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Using the continuation package AUTO [7], and closely following the techniques outlined in [5], the nonsingular canard, Ξ t, is found for τ s = 15 and is then continued in τ s.
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For our numerical investigations, we used the continuation package Auto[55, 56] for solving the boundary value problems.
Then the uniqueness of the solution on [ 0, T ] is direct using the continuation property.
This four-category response was modelled using the continuation ratio approach to ordinal data.
A second approach is to use the continuation method.
Using the bifurcation package AUTO [18], a continuation in the two model parameters for the saddle-node on invariant cycle (SNIC) points of the periodic orbits allows for some speculation on the genesis of such intriguing, high-order phenomena.
The IDMC will review the treatment failure-free rate, along with toxicity and feasibility, before they endorse continuation into Stage 2. Calculations were performed using the ART package [ 44] in Stata 9 assuming a 3 year recruitment period followed by 1 year of follow up (based on a 2-sided log rank test).
The statistical analysis were performed using the R statistical package and the effsize package (Torchiano 2017).
Data were analyzed using the R package.
Solubility and supersaturation were calculated using the software package EQ3/6.
Analysis was done using the same package.
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