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The murmur propagation in a realistic model of a human thorax is also simulated by using the computational method.
Our surface-cavity design strategy showed that flexible surface residues tolerant to mutations are valid targets for thermostabilization with no reduction in catalytic activity, and that local-interaction stabilization of cavity-lining residues using the computational method can be an effective alternative to the conventional cavity-filling method.
Using the computational method of molecular dynamics, the laboratory of Benoît Roux, Professor of Biochemistry and Molecular Biophysics, compared closely how Gleevec binds and affects Abl and a different tyrosine kinase called Src.
For this task we ranked gene pairs according to their synergy [ 9] with COL11A1, using the computational method in [ 19], which could further facilitate biological discovery.
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For example, some determinants for the improved thermostability of a mesophilic GHF11 xylanase, AuXyn11A, were predicted using the computational methods (Zhang et al. 2014).
It can be shown using the computational methods described in the 'Methods' section that the only possible sparse realization structure is identical to that of the original network.
Results showed that some of the ligands designed using the computational methods had better docking energies than peptides designed using a purely chemical knowledge-based approach [ 61].
Using the computational methods available at http://www.microrna.org and miRBase (http://microrna.sanger.ac.uk/), we identified Bcl-w as the potential target for miR-205, and E2F6 as the potential target for miR-31.
Authors used the computational method to simulate the blood flow inside of the cannula.
We used the computational method to elucidate the connections between a well-known driver gene of intestinal cancer, Apc (adenomatous polyposis coli), to another gene also involved in cancer, Cdkn1a (previously known as p21).
The hydroPSO function uses the computational method of particle swarm optimization (PSO) that optimizes a problem by iteratively trying to improve a candidate solution with regard to a given measure of quality.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com