We used the computational algorithms miRanda, PicTar, and TargetScan to identify prion-related potential target genes of the de-regulated miRNAs based on seed-sequence homology with 3' UTRs of mRNA transcripts [26] [28].
We used the computational algorithms of SIFT, AlignGVGD, Polyphen and Mutation Taster for missense varaints and the splice site prediction programs SpliceSiteFinder, MaxEntScan, NNSPLICE, GeneSplicer and Human Splicing Finder for intronic, silent and missense variants.
To explore the potential biological function of miR-107, we then identified validated targets using the computational prediction algorithm from miRWalk [ 24].
We determined binding hot spots in the PPARγ LBD using the computational solvent mapping algorithm FTMap (Brenke et al. 2009).
Within a class, the proposed scheduling policy computes the resource allocation "chunk-by-chunk" leading to a high computational complexity; the computational complexity of such schedulers can in fact be reduced significantly by using the fast computational algorithms presented in this paper.
Examples using these models and the computational algorithms in a virtual laboratory environment are used to demonstrate the utility of this unique database and simulation technology.
These transcripts were then validated independently using the cuffdiff computational algorithm [ 14].
This work presents some of the computational algorithms used for phasor estimations in Electrical Power Systems.
It should be kept in mind however, that the computational algorithms used for the demographic modeling are designed for models involving an ancestral population which split and maintained constant migration rate among the two daughter populations.
Although we are aware that the intensive sampling described here may not always be feasible, we would like to note that including field epidemiological information to guide the computational algorithms used to infer relationships among populations was key to the success of the analysis and should become a common practice when attempting to reconstruct the invasion history of an exotic organism.
