We used the coefficients given in Table 3 to construct a tool for predicting if an index patient would have caused transmission by the time he/she is identified and isolated.
Specifically, we determine the coefficients related to the first and second subbands in Equation (74) from the elements of coefficient vectors in Equations (25), (42), and (56) using the coefficient selection rule given in Subsection Coefficient Selection Rule for Process Parameters in Four-Channel ARMA Lattice Prediction.
Therefore, we correct the offsets using the coefficients from Muscheler et al.37.37
To reconstruct the coefficient in position (u,v), the optimal reconstruction proposed in [14] is used, which is the expectation of the coefficient given that the available SIs are the following: C R e c b k u, v = ∫ L U x f F u s b k, u, v x d x ∫ L U f F u s b k, u, v x d x (15).
Step 4: Solve equivalent single-objective MILP model using the given coefficients (θ h,γ).
The buried and exposed residues thus identified were assessed by calculating sensitivity and specificity values for the two classes of the residues namely buried and non-buried (exposed), and the overall accuracy as well as the correlation coefficient using the expressions given in the Methods section.
Chlorophyll concentrations were calculated by the absorbance spectra of the extract at 647 and 663 nm, using the formula and extinction coefficients given in Porra et al. [48].
Moreover, using the information given in this reference, kappa coefficients can be calculated, which are different from the coefficients found in this study (kappa coefficients of 0.28, CI −0.05-0.60 for nares and 0.80, CI 0.64-0.97 for throat).
In this case, a ROC analysis for selection of relevant predictors, using PLS regression coefficients, gave a ROC-AUC value of 0.67 (data not shown), as compared to 0.98, when relevant predictors were grouped into a cluster of X (results were averaged on 100 replications of the above simulation).
Chlorophyll a, chlorophyll b, and total chlorophyll were estimated following Arnon's method using the specific absorption coefficient given by Mackinney in 1941 [18, 19].
