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The required sample size for a definitive trial will be calculated using the clinical outcome data from the pilot trial.
Kaplan-Meier survival analysis was performed using the groups that emerged from this K-means clustering and using the clinical outcome data (vital status).
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Because of the close agreement between the two WHO systems for assessing therapeutic outcomes only the results using the clinical outcomes as defined in the WHO 2003 system are reported.
(g) Subjective well-being: is assessed using the Clinical Outcomes in Routine Evaluation – Outcome Measure (CORE-OM [ 73]).
Clinical severity at baseline was measured using the Clinical Outcomes in Routine Evaluation - Outcome Measure (CORE-OM) [ 34], comprising four subscales of wellbeing, symptoms, functioning and risk.
The main advantage of conducting a CEA, rather than a CUA or CBA, is that these studies can use the clinical outcome measured during the effectiveness trial.
Regardless of whether treated (chemical, freeze dried, irradiated) or fresh-frozen non-irradiated allografts are used, the clinical outcome is usually good [ 5- 7].
26 We used the clinical outcomes in routine evaluation-outcome measure (CORE-OM) 27 as a measure of global distress.
However, reduced redislocation rates are so far not necessarily reflected in the clinical results, at least not when the Kujala score is used as the clinical outcome measure (Wang et al. 2016; Saccomanno et al. 2016; Erickson et al. 2015), a limitation that will be discussed later.
To describe etiologic agents, the antibiotic use and the clinical outcome of pneumonia patients who require mechanical ventilation.
Using the available clinical outcome data, Kaplan-Meier analysis was performed on the patient groups defined by the hierarchical clustering analysis.
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