Sentence examples for using the cellular model from inspiring English sources

Using the cellular model of neuronal atrophy caused by DYNC1I1 deficiency, we are able to identify that RAS-RAF-MEK signaling, but not PI3K-AKT signaling, protects neurons against dendritic atrophy in primary hippocampal neurons, and reveals that RAS-RAF signaling activates MEK-dependent protective autophagy.

In addition to testing of toxicity on cellular level, we decided also to investigate in greater detail the molecular mechanisms of action of studied complexes using the cellular model system based on the LPS-activated respiratory burst in phagocytes and its effect on the inflammatory cytokine expression.

Concentration response curves of lead compounds were generated using the cellular model systems and exogenous assay for the human isoforms or using the modified Amplex Red assay and exogenous assay for PldA (Table 2).

Cell motility, adhesion and biophysical constraints can be added using the cellular Potts model (CPM) framework (Graner et al., 1992).

These storylines are translated into spatial planning strategies and modelled using the cellular automata model LUCIA.

Starting from a rough initial guess, the individual cell wall positions predicted by simple image processing in a liquid foam are refined using the Cellular Potts Model in Fig. 2 by minimizing the surface tension.

Future work will focus on using the cellular and animal models of RTT to identify the optimal agent to move into human clinical trials.

Primary cultures of phytohemagglutin (PHA -stimulated sPHA -stimulated usplenocytescellular model.

The kinetics of the restoration processes that take place during the isothermal annealing of metals for the case when the critical strain for the onset of dynamic recrystallization is reached and exceeded were modeled using the Cellular Automata approach.

Second, computational modeling of the influence of glycocalyceal charge upon intracellular ionic homeostasis was performed using the CD cellular model of Fraser and Huang (5).

Using this cellular model, for the first time, embryonic development could be studied under in vitro conditions, but definitive pluripotency, that is in vivo development into both somatic and germ line cells, has not been shown.