Your English writing platform
Free sign upSuggestions(1)
Similar(60)
Using the 'Cellular Component' and the 'Molecular Function' ontologies, we investigated the repartition of protein localizations and molecular functions in each PRODISTIN class (see Methods for details, Figure 2a and 2b).
There are three non-overlapping ontology domains, so that gene products may be categorized according to GO terms representing the molecular functions they carry out (using the Molecular Function ontology), the cellular locations where they act (using the Cellular Component ontology), and the biological processes in which they take part (using the Biological Process ontology).
GO term enrichment analysis was used to measure the cellular functions of identified pathways as performed in previous studies (Carbon et al., 2009; Yi and Stephens, 2008).
Besides the fact that the overexpression of USP17 subfamily proteins induces apoptosis in cancer cells, the ability to bind with hyaluronan is another important point used to elucidate the cellular functions of USP17 subfamily proteins.
A number of studies have attempted to understand the cellular function(s) of dysbindin using cell lines and primary cell cultures.
In the case of the cellular function filter, we have used the distance as the underlying parameter for plotting the ROC curve (Figure 1A).
The Ingenuity Pathways Analysis program (http://www.ingenuity.com/index.html) was used to further analyse the cellular functions and pathways that were significantly regulated by Snai2 in response to DNA damage.
The proteome broadly defines all the cellular functions used by the organism.
As these kinases all play roles in regulating MCF7 proliferation and/or survival, these inhibitors cannot be used in isolation to determine the cellular functions of RET.
We carried out the same tests using the Molecular Function and Cellular Component sub-ontologies, which gave similar results.
The test analysis shows that there is value in using molecular and cellular function filters for reducing false-positives in minimotif predictions.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com