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Subsequently, hits identified by mass spectrometry were further filtered and the data were checked for enriched proteins forming a complex with Hsp60 [36], We also assessed for enrichment in published interactors using the BioGRID database [37].
The genetic network was initially built using the BioGRID database.
Among these four pairs of TFs studied, we also validated their interaction using the BioGrid database.
Here we applied a statistical model combining hypergeometric distribution and logistic regression to increase the coverage of membrane proteins, using the BIOGRID database as a reference.
A potential limitation of the current evaluation setup is the definition of the reference set of interactions using the BioGRID database.
As an alternative approach to the analyses, we used g:Profiler (Bioinformatics, Algorithmics and Data Mining Group 2011), which interprets gene lists by identifying enriched protein protein interactions using the BioGRID database (BioGRID 2011).
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We used the BioGRID database to create a ranked list of genes that had similar genetic interactions to EXO1 (Stark et al, 2006).
So to collect the data of recent experiments we used the BioGRID database (The Biological General Repository of Interaction Datasets), release 3.1.72 December 25thh, 2010), which is updated monthly and archives genetic and protein interaction data from model organisms and humans including S. cerevisiae.
We repeated the same analysis by using data from the BIOGrid database (with only links that are supported either by low-throughput experiments or by more than a single high-throughput experiment).
In HTSanalyzeR we use networks defined in the BioGRID database (Stark et al., 2006), but other user-defined networks can easily be included in the analysis.
In addition to the E-MAP dataset used in the present analyses, the BioGRID database contains genetic interactions extracted from three other large-scale screening studies performed with the E-MAP approach [ 4, 6, 7].
More suggestions(15)
using the ProfCom database
using the MicrobesOnline database
using the Ingenix database
using the biogrid high-confidence
using the BioRag database
using the biogrid cut-off
using the Mascot database
using the biogrid protein-protein
using the biogrid Import
using the biogrid package
using the Amadeus database
using the biogrid protein
using the Oncomine database
using the Webribo database
using the SortMeRNA database
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