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To control for this, the data were re-analysed 999 times using random permutations of the patient outcome labels to generate true (permuted) P-values for each gene set.
The decoy sequences are generated using random permutations of the original peptide sequence.
The occurrence of this pattern was tested using random permutations of allele sizes among allelic states [ 29].
Next, 10 bootstrap replicates of the slope parameter are computed using random permutations of the observed rates at those trials.
The number of genes/exons/introns expected to have a given rank product by chance was estimated using random permutations of the rank lists.
The final best match for each predicted matrix was selected from these by using random permutations of each MEME matrix to estimate statistical significance (see below).
Similar(51)
The statistical significance of misclassification error was determined using random permutation of samples (N = 1,000).
This is due to the fact that the method uses random permutations of the phenotypic status of the subjects in the sample to assess the significance of the enrichment score.
The observed vi or vj indices are tested using random permutations against the H0 of complete spatial independence of counts [ 66].
Most of the gene-set methodologies use random permutations to assess the statistical significance of the results.
Using random permutation, we get 32 positive results from 5000 permutations, corresponding to a permutation p-value 0.0064.
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