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In a meta-analysis using PET for tumour response, Kwee found a pooled sensitivity of 67% and specificity of 68% and concluded that PET should not yet be used routinely to guide neoadjuvant therapy decisions.
There are several reports using PET, for example [15], [16], [17], [18], [19] but rather than examining the ongoing clinical pain per se, several of these studies have examined CBF changes in response to an experimentally-derived nociceptive stimulus in addition to any ongoing background pain.
When compared with CT alone, the additional costs per life-year gained were €2,508 when using PET for indefinite CT and €415 when using PET for all.
The greatest difficulty in using PET for colonic abnormalities is the presence of physiologic uptake in the gastrointestinal tract.
Striatal dopamine transporter (SDT), which mediates the actions of many drugs, has been investigated using PET for diseases including drug abuse.
Interest also exists in using PET for studying opioid biochemistry and opioidergic neurotransmission in epilepsy, pain processing and neurodegenerative disorders, including its use for evaluation of more selective, improved analgesics, anticonvulsants and neuroprotective agents.
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The large body of literature correlating FDG-PET with nodal pathology in NSCLC makes it rational to use PET for designing mediastinal radiation fields.
Of these, most have used PET (for example [ 10, 12]).
These include: When is the best time to use PET for response assessment?
Delforge et al. [ 25] used PET for in vivo quantification of cardiac β-adrenergic receptors and was able to obtain their density maps.
Back in the "newspaper age," some humane organizations warned that newspapers are as likely to attract people who want to use pets for unethical purposes, as they are to reach responsible pet-owners.
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