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Using mouse models of melanoma, Li et al.
Green propolis from the southwest of Brazil was tested using mouse models of pain and inflammation, as well as in in vitro cell cultures.
Much work has been done using mouse models of global ether lipid deficiency, revealing gross abnormalities associated with such manipulations (da Silva et al., 2012).
The present study has been designed to pharmacologically expound the significance of inducible nitric oxide synthase in the pathophysiological progression of seizures using mouse models of chemically induced kindled epilepsy and status epilepticus induced spontaneous recurrent seizures.
Using mouse models of LGA (maternal high fat (HF) diet) and SGA (maternal low protein (LP) diet) offspring, our lab has previously shown that these offspring display alterations in the expression of mesocorticolimbic genes that regulate dopamine and opioid function, thus indicating that these brain regions and neurotransmitter systems are vulnerable to gestational insults.
Herein, we characterize an influential role for the saeR/S two-component gene regulatory system in mediating cytokine induction using mouse models of S. aureus pathogenesis.
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The anti-amnesic potential of the most active extract (i.e. 70% methanol extract of G. mediosinense) was confirmed using mouse model of scopolamine-induced amnesia.
This is consistent with the observation of our previous study using mouse model of oral candidiasis in vivo [ 27].
The mechanism by which our patients had relapse, if different from historical patients, may be elucidated by further study using mouse modeling of hematopoietic transplant.
The antidepressant-like effect of chiisanoside from the leaves of Acanthopanax sessiliflorus was evaluated by using mice models of depression, forced swim test (FST) and tail suspension test (TST).
By using mice models of breast cancer, they found that treatment of tumor bearing mice with either anti-CD73 mAb or APCP decreased tumor angiogenesis [ 45].
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