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Although many researchers have monitored the response to imatinib in CML patients using molecular methodologies and cytogenetic techniques [7], [9], [10], no comprehensive metabonomic investigation has been made of the responses of CML patients to imatinib.
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These researchers identified disproportionally high rates of ceftazidime resistance amongst P. aeruginosa isolated from their pediatric population and subsequently genotyped all isolates using molecular methodology identifying 85%% of patients harbored the same strain, the Liverpool Epidemic Strain LESS).
Future research connected to this field should use molecular methodologies capable to increase the level of taxonomic resolution.
Since then, our group has used molecular methodology to identify all PSMs present in S. aureus and S. epidermidis on the gene and protein level.
In that fateful summer of 1992, Prasher moved from WHOI to the U.S. Department of Agriculture's Animal and Plant Health Inspection Service APHISS) lab, on Cape Cod in Massachusetts, where he worked on identifying pests "using molecular and biochemical methodologies," he says.
The sequencing of the mutant genomes permits further qualitative analysis which may be missed using molecular biology methodologies resulting in falsely linking a retrieved gene sequence to a phenotype.
It has been hoped that these questions may be answered, and a timescale for animal evolutionary history established, using molecular clock methodology.
The main advantages of using molecular docking methodology are to analyse the binding modes of the ligand with the target, compare binding energies of various ligands, and estimate stability of docked ligand-target complexes.
The success of this model prompted us to use it to test the efficacy of the protocol we have established for infection detection using molecular biology methodology ([6],[8]; Mariani et al. 1996b; [7],[1996b1996b
In this work we present a methodology to produce nanoporous carbon structures, using molecular dynamics simulations and a many-body potential.
Putative species delimitations have been determined here without prior assumptions and we propose a suitable methodology using molecular data from holotypes to assign the right name to each delineated species.
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