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Pioneer designs lots of famous under-actuated robotic hands using linkage, tendon and gear transmissions [17, 18, 19, 20].
Genome-wide scans using linkage and association methods have identified a number of suggestive genomic regions that are pending replication.
The tag-SNPs were selected using linkage disequilibrium as detailed in the methods section.
Several genes were found to be associated with NRG under Al stress and subsequently confirmed using linkage analysis.
This study might have been underpowered to detect genes with smaller effects, since very large sample sizes are required to detect small effects using linkage analysis [45].
This method is implemented in LDNe [83] and allows using linkage disequilibrium to estimate Ne even when sample size is small.
Recombination within housekeeping genes was tested using linkage disequilibrium estimated between loci [29], a coalescent-based likelihood permutation test, LDhat [54] and the PHI test [55].
Fine mapping of this region using linkage disequilibrium association mapping and potentially functional SNPs revealed association of the -2518 MCP-1 SNP the with disease [1].
While this could not be directly tested with the current data set, studies are currently underway to test this hypothesis using linkage mapping and physiological manipulations.
Familial cancer is rare in comparison to non-hereditary cancer, but a number of recessive genes have been identified using linkage analysis [11], [12].
Found homologs were grouped using linkage clustering (-lscut = 0.9), and representative sequences from each group were used as transitive queries for subsequent rounds of PSI-BLAST.
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