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Central banks have been using large doses of experimental drugs, and nobody knows for sure whether there will be hazardous side-effects.
By Miami, where Cuban-Americans are an influential voting bloc, Mr. Bush and his brother were using large doses of Spanish in their speeches.
Recent reviews have raised concerns about the safety of using large doses of β2-agonists, especially in patients with underlying cardiovascular comorbidity [27 29].
Recent reviews have raised concerns about the safety of using large doses of β2-agonists, especially in patients with underlying cardiovascular comorbidity.
Instead of using large doses of pharmacological agents to inhibit or suppress symptoms, very small and specially prepared doses of medicinal substances are individually prescribed to a person for their unique ability to cause in overdose the similar symptoms that the sick person is having.
The dosing is adjusted according to the clinical response of the patient, but large doses may be needed in severe cases (there is a risk of precipitating metabolic acidosis due to the preservative propylene glycol when using large doses of diazepam).
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It is possible that using larger doses of heparin may result in a better control of bleeding.
In the phase I study using larger doses of sorafenib, 600 and 800 mg twice daily, skin rash, hand foot syndrome, diarrhea, nausea, hypertension, and fatigue were observed as the most common adverse events.
On the other hand, the FDA has just advised against using larger doses of quinine, found in the drug Qualaquin, to treat muscle cramps.
Not many people, for example, are aware that computerised tomography (CT) scanning uses large doses of X-rays.
Last season, when the Jets used large doses of the spread offense early in the season, the offensive line and the running game suffered because the line could not get into the rhythm of run blocking.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com