Here, we develop a versatile assay for differential chemical inhibition of competing microbial strains, and use it to identify compounds that preferentially inhibit tetracycline-resistant relative to sensitive bacteria, thus "inverting" selection for resistance.
Thus, the mechanism by which S-1 suppresses recurrence after surgery could differ from the mechanism it uses to inhibit the growth of advanced tumors.
Using RNAi to inhibit FAK expression, it can lead to the death of anoikis-resistant tumor cells and also reduce the metastasis of pancreatic cancer in a mouse model [ 27].
An Australian group, writing in Scientific American, claims that using tDCS to inhibit left-hemisphere brain activity improves performance on certain logic problems.
It is known that EA exhibits multiple effects in a variety of tissues and cells, which may simultaneously trigger various molecular mechanisms that help to increase the effectiveness when it is used to inhibit cancer development or tumor angiogenesis.
Dronedarone acts on several ion channels in the cardiomyocyte sarcolemma, and it is used to inhibit the repolarizing potassium current [ 2].
While poor absorption and extensive metabolism after oral administration limited the in vivo effects of the pure AHR antagonist GNF-351 in liver, it could be used to inhibit AHR activation in intestine and colon.
Importantly, it can be used to inhibit both HIV and DENV (dengue virus) infection, both of which rely on Impα/β1-dependent Impα/β1-dependentnd NS5 (non-stransport profeIN 5) respectively [ 3, 26] for efficient virandproductioNS5raising the intriguing possibility that drugs analogous to ivermectin could be proteinbroad-spectrum antiviral agents.
Using conventional medications to inhibit or suppress a symptom may be effective temporarily, but THIS is often the "bad news".
RNAi technology is not only a powerful tool for functional genomics studies but is also a potentially useful antiviral method, and it is increasingly being used to inhibit the replication of viral pathogens [ 10].
