For the population that consisted of large half-sib families, there was no difference in genetic gain when using pedigree or genomic measures of relationship to constrain inbreeding.
In summary, homogeneity in prokaryotic genomes, measured using genomic signatures, is highly associated, in order of importance, with bias in DNA composition, as measured by the OUV measure, AT content, phyla and oxygen requirement.
Therefore, genomic libraries enriched with CA, GA, AAC and AAG repeats were constructed using genomic DNA of P. vera cv.
Genetic merit was further increased using genomic rather than pedigree-based measures of co-ancestry under an inbreeding restriction policy.
Regression analysis revealed that OUV was the most important factor (p<0.001) determining intra-genomic homogeneity as measured using genomic signatures.
For the genomic line, genomic measures of inbreeding were calculated using PLINK [ 17], including average homozygosity, number and size of homozygosity runs of at least 50 consecutive SNPs, and inbreeding coefficients based on expected vs. observed homozygosity.
Genomic measures of inbreeding can be used instead of pedigree-based inbreeding to estimate the effects of inbreeding depression and give similar estimates.
Comparing prokaryotes using genomic signatures can be considered as a measure of how DNA words are over- or underrepresented within genomes from what is expected from genomic AT content alone.
Hence, the OUV measure approximates genomic oligonucleotide frequencies using genomic AT content.
Phylogeny of Gossypium using genomic CenH3 sequences.
