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Future research can thus be devoted to untangling the temporal dimension of effects such as meaning frequency, ROM, and contextual congruency using different experimental paradigms.
A decrease in OR availability related to acute pain has so far been demonstrated by three independent research groups, each using different experimental paradigms (muscle, capsaicin and heat pain) (Zubieta et al., 2001; Bencherif et al., 2002; Sprenger et al., 2006 a ).
On the other hand, there is an impressive number of studies available concerning the effects of dietary sugars, using different experimental paradigms, with different approaches, animal models, oral intake doses, in the form of sugar solutions or added in the diet, or peripheral or central administrations.
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BoNT-A (onabotulinumtoxinA, BOTOX®) effects on meningeal nociceptors were studied using four different experimental paradigms.
The use of different experimental paradigms or estrogen treatment regimens may contribute to these disparate findings.
This highlights the robustness of the effect which has now been demonstrated using a number of different experimental paradigms [1] [3].
This result is in line with previous studies using donepezil pre-treatment in different experimental paradigms.
A relationship between hypoxia inducible factor (HIF) and PACAP was described in several studies in different experimental paradigms [53 55].
It is notable that behind the apparently conflicting results are different experimental paradigms.
Behavioral manifestations of these competitive interactions have been observed in a number of different experimental paradigms [3] [7].
Two different experimental paradigms were designed to investigate the role of background noise and cell memory in spike time precision.
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