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Haplotype information is useful for many genetic analyses and haplotypes are usually inferred using computational approaches.
But using computational approaches to understand their activity first requires gathering an enormous amount of data, which Regev has long done through RNA sequencing.
Using computational approaches to Integrate clinical, biological, genomic and proteomic data to identify new molecular phenotypes of disease.
In the Department of Ecology and Evolutionary Biology, Assistant Professor Iain Couzin is using computational approaches to understand how complex behaviors such as bird migrations and insect swarms emerge out of actions and interactions among individuals.
Using computational approaches to explore our gene-expression data sets, we found that NRAS(G12V) enforced the leukemia self-renewal gene-expression signature and was required to maintain an MLL-AF9 and Myb-dependent leukemia self-renewal gene-expression program.
His laboratory has taken a systems-level approach to understanding cellular behavior by making large-scale global observations and using computational approaches to infer the key underlying components and their organization into regulatory and genetic networks.
His research is at the intersection of systems biology, bioinformatics and artificial intelligence, and aims to understand how biological cells work and react to drugs and environmental signals using computational approaches.
As a result, the irresistible rush towards using computational approaches has focused on dimensionality reduction and the convenient representation of high-dimensional data sets.
Recent modeling efforts to increase the fracture resistance of intermetallic and in-situ composites using computational approaches to identify alloying effects are summarized.
Using computational approaches, we define genomic and proteomic features associated with MYC and the PMN across the 33 cancers of The Cancer Genome Atlas.
The present work is to identify lead molecules for Flavivirus NS5 MTase using computational approaches like structure-based pharmacophore and induced fit docking.
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