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To bridge the gap, using approaches that require extensive handcraft implementations such as hard-coding in general purpose programming languages like Java will give rise to the programming complexity.
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We combined markers using approaches that did not require statistical fitting because of the low sample sizes.
Just as using DNA constraint as a sole criteria for enhancer finding has its limitations, using filtering approaches that require conserved combinatorial binding will also miss important regulatory events near genes of interest.
We have now included this important point in the Discussion, with the text starting "Just as using DNA constraint as a sole criterion for enhancer finding has its limitations, using filtering approaches that require conserved combinatorial binding will also miss important regulatory events near genes of interest".
Furthermore, for the class of Bayesian-network structures for which the two assumptions are compatible, we can learn the optimal solution using standard approaches that require only O(n2) calls to an independence oracle.
In terms of lack of time, busy undergraduate students may not be used to teaching approaches that require them to do homework that goes beyond textbook reading, such as viewing a lecture and/or writing responses to assessment probes before coming to class.
Our method has the potential to identify novel associated genes; provide a basis for selecting SNPs for replication; and be directly used in network (pathway) approaches that require per-gene association test statistics.
Two different approaches are currently used to evaluate human machine interfaces, empirical approaches that require user involvement in the interface development process, and analytical approaches that do not associate the user during the interface development process.
To illustrate its practical application for transitional flows, the LKE model is coupled with an existing k−ω model using a new approach that requires minimal modifications.
This can be done using an interpretative approach that requires contextualization of differences to meaningfully inform environmental monitoring programs and provide focus for action.
Kim et al. [30] used a modified approach that required the final number of ESTs in the compared organisms' genes to be the same to mitigate the bias in data availability for the studied species.
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