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The length density of the myelinated fibers in the cortex was estimated using an unbiased counting frame.
Counts of TH+ varicosities were made at regular predetermined intervals (x = 150 µm, y = 150 µm) using an unbiased counting frame of known area (6 µm×6 µm = 36 µm2).
Briefly, systematic random sampling of sites was undertaken using an unbiased counting frame (100 μm × 100 μm).
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Vessel density was counted on CD34 and CD105 immunostained slides, according to conventional stereological methods using an unbiased Gundersen counting frame (Gundersen, 1978).
The number of bacteria in the vacuole was estimated using an unbiased stereological approach31 by counting bacteria in five probes across a series of 55 TEM sections cut through the middle of a single vacuole.
Here, using an unbiased systems biology approach we report a unique role for a PRC2 accessory protein.
We estimated the number of objects in this case, bacteria in the CV using an unbiased stereological approach31.
Using an unbiased yeast genetic screen we discovered Dbr1 as a potent suppressor of TDP-43 toxicity.
First, we tested all SNPs using an unbiased association design.
Using an unbiased transcriptomics approach, we found that cardiac glycosides inhibit general protein synthesis.
In this study, we surveyed tyrosine kinase signaling events in cholangiocarcinoma using an unbiased phosphoproteomic approach.
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