The fundamental difference between these two methods is that the 2S one uses an explicit reference, while the 1S one does not use any explicit reference.
They should only be used with an explicit reference to the audience about its limitations.
To make as accurate inferences as possible, the GO Consortium's Reference Genome Project is using an explicit evolutionary framework to infer annotations of proteins from a broad set of genomes from experimental annotations in a semi-automated manner.
Hickey et al. [ 4] compared two strategies to include phenotypes of ungenotyped individuals in the reference population, i.e., prediction using an explicit imputation step and prediction using an H-matrix.
Because the fluid simulations do not make use of an explicit reference configuration, strain is computed by integrating strain rate and advecting the results.
The Arab League adopted a resolution urging action against the Syrian government for what it called the "ugly crime" of using chemical weapons, but it stopped short of an explicit reference to military intervention.
Notwithstanding the absence of an explicit reference to race in the literacy tests themselves, their use was a case of direct discrimination.
It also included an explicit reference to land-grabbing.
Nowhere in Cardinal Baum's letter is there an explicit reference to homosexuality.
Cameron tried and failed to have an explicit reference to no-fly zones and Nato in the summit statement.
