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In this study, a pharmacokinetic investigation was performed using an administration of dexamethasone, which has well-established pharmacokinetic properties [ 19, 20].
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Recent studies [20 24] using a single administration of 1.11 GBq of 131I report thyroid remnant control probabilities ranging from 70 to 95%%, i.e., mathrm{T}mathrm{C}mathrm{P}left(1.11 mathrm{GBq}right)in left[0.70, 0.95right] (4).
The effects of increasing the time interval between Cd administration and initiation of chelation therapy was determined by using a single administration of DTPA, EDTA, and DMSA.
We did, however, achieve similar findings using a single administration of Nec-1s immediately before ConA or APAP administration, suggesting that excessive dosing of inhibitors does not account for our findings (not shown).
Immune challenge was induced by the injection of sheep red blood cells (SRBC) and corticosterone levels were increased using a transdermal administration of corticosterone.
Concerning intratracheal aerosolization, the oropharynx was first anesthetized using a local administration of lidocaine.
A phase I/IIa trial of AdCD40L by Uppsala University used an intravesical administration of an adenovirus vector to upregulate the human CD40 ligand in MIBC patients scheduled for cystectomy [ 33].
The protocol of the first regimen used a daily administration of cisplatin (10 mg/body) for 1 h followed by 5-FU (250 mg/body) for 5 h on days 1 5.
In 2009, Kota et al (Kota et al, 2009) used a systemic administration of miR-26a in a mouse model of HCC using adeno-associated virus (AVV) to inhibit cancer cell proliferation and induction of tumour-specific apoptosis.
We used a single administration of clomiphene citrate (CC), a synthetic oestrogen that is prescribed for infertility treatment, in combination with either a single administration of oestradiol 17 (E2) or progesterone (P4) to assess the combined effects of these hormones on the uterine surface.
If applied in humans, it will be possible to use a single administration of gene therapy to provide long-term prophylaxis against secondary coronary events and to promote myocardial repair in patients who have experienced an infarct, as well as in those at high risk of myocardial injury.
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