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The landscape value is obtained using an additive value function.
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To estimate h L 2, the proportion of phenotypic liability variation which can be attributed to common SNPs, we first use LDAK (Speed et al., 2012) to calculate a kinship matrix based on allelic correlations across autosomes, using an additive encoding of SNPs, with values centred and scaled to have mean zero and variance one.
For argon and silicon experiments, measured damage in the mixed radiation field was consistent with the value expected using an additive function for low- and high-LET separated data.
The SNP with the best evidence for an association (rs772921, #8) had a p-value of 4×10−11 and OR = 1.43 as estimated using an additive logistic regression model.
Alternatively, weight adjustment could be performed using an Additive Increase/Additive Decrease- (AIAD-) based algorithm.
All meta-analyses were performed using an additive model.
OHIP-14 total scores were calculated using an additive method.
Random residual error was described using an additive model.
Although the use of ITNs alone has been shown to reduce morbidity and mortality due to malaria [8], [9], there is an additive value when used together with effective antimalarial medicines, indoor residual sprays and environmental management.
Further studies should clarify, if an adjuvant therapeutic use of CD24 antibodies may have an additive value in cancer treatment.
A probabilistic MCDA model with an additive value function was developed and illustrated using a case on hypothetical treatments for depression.
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